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Article

The Spanish Polygenic Score reference distribution: a resource for personalized medicine.

European journal of human genetics : EJHG - 1 Feb 2026

Carmona Rosario, Roldán Gema, Fernández-Rueda Jose L, Navarro Arcadi, Peña-Chilet María, Dopazo Joaquín, López-López Daniel

Abstract excerpt

Here we present the Polygenic Score (PGS) distributions for 3124 common diseases and quantitative traits observed in the Spanish population. To achieve so, the genomes and exomes of 2190 unrelated individuals of Spanish ancestry were used. The analysis covered a wide range of diseases and traits, including both complex disorders, such as various types of cancer, and disorders associated with the digestive,...

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Identifiers

PMID: 40275119
DOI: 10.1038/s41431-025-01850-9
PMCID: PMC12859145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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