Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FOXR2 activation is not exclusive of CNS neuroblastoma

15 Apr 2025

Abstract excerpt

BACKGROUND: FOXR2 activation is regarded as pathognomonic for CNS neuroblastoma (NB). However, a comprehensive understanding of the landscape for CNS tumors exhibiting FOXR2 activation is lacking. METHODS: Histopathologic, molecular, imaging, and clinical data of 42 CNS tumors with FOXR2 overexpression identified through screening institutional datasets and published institutional cases were analyzed. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Glioma Diagnosis and Treatment
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40237561
DOI: 10.1093/neuonc/noaf076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FOXR2 activation is not exclusive of CNS neuroblastomaPMID 40237561Read ↗

Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activationSemantic proximity Read ↗

Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities: results of an international, retrospective studySemantic proximity Read ↗

A human embryonic stem cell–based model reveals the cell of origin of FOXR2-activated CNS neuroblastomaSemantic proximity Read ↗

Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype.Semantic proximity Read ↗

Pineal region glioblastomas display features of diffuse midline and non-midline gliomas.Semantic proximity Read ↗

Embryonal tumors of the central nervous system.Semantic proximity Read ↗

Differences in regional developmental origins of glioblastomas revealed by integrated molecular profiling.Semantic proximity Read ↗

Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study.Semantic proximity Read ↗

Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas.Semantic proximity Read ↗

Genomic medicine and neuroblastoma.Semantic proximity Read ↗

AT-21INTEGRATED (EPI)GENOMIC ANALYSES IDENTIFY SUB-GROUP SPECIFIC THERAPEUTIC TARGETS IN CNS RHABDOID TUMORSSemantic proximity Read ↗

Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.