Article
Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study.
Acta neuropathologica - 1 Feb 2020
Li Bryan K, Vasiljevic Alexandre, Dufour Christelle, Yao Fupan, Ho Ben L B, Lu Mei, Hwang Eugene I, Gururangan Sridharan, Hansford Jordan R, Fouladi Maryam, Nobusawa Sumihito, Laquerriere Annie, Delisle Marie-Bernadette, Fangusaro Jason, Forest Fabien, Toledano Helen, Solano-Paez Palma, Leary Sarah, Birks Diane, Hoffman Lindsey M, Szathmari Alexandru, Faure-Conter Cécile, Fan Xing, Catchpoole Daniel, Zhou Li, Schultz Kris Ann P, Ichimura Koichi, Gauchotte Guillaume, Jabado Nada, Jones Chris, Loussouarn Delphine, Mokhtari Karima, Rousseau Audrey, Ziegler David S, Tanaka Shinya, Pomeroy Scott L, Gajjar Amar, Ramaswamy Vijay, Hawkins Cynthia, Grundy Richard G, Hill D Ashley, Bouffet Eric, Huang Annie, Jouvet Anne
Abstract excerpt
Pineoblastomas (PBs) are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical and molecular spectra of PB to inform new treatment approaches for this orphan cancer. Tumor, blood, and clinical data from 91 patients with PB or supratentorial primitive neuroectodermal tumor (sPNETs/CNS-PNETs), and 2 pineal parenchymal...
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