Article

AT-21INTEGRATED (EPI)GENOMIC ANALYSES IDENTIFY SUB-GROUP SPECIFIC THERAPEUTIC TARGETS IN CNS RHABDOID TUMORS

2016-06-01

Abstract excerpt

Atypical Teratoid Rhabdoid Tumors (ATRTs) are the most common malignant embryonal brain tumors arising in younger children that are distinctly lethal cancers for which effective therapies are lacking. In this study, we integrated whole genome/exome/transcriptome sequencing as well as methylation and nucleosomal profiling analyses to comprehensively define the genomic and epigenomic landscape of ATRT sub-groups and...

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Literature Corpus work: 3095dc2a-a66b-5e0e-96e0-e4a2039d8d31
DOI: 10.1093/neuonc/now065.20

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