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Trop-2 expression in non–small cell lung cancer

15 Apr 2025

Abstract excerpt

Trophoblast cell-surface antigen 2 (Trop-2) is highly expressed in non-small cell lung cancer (NSCLC) and has become an attractive target for antibody-drug conjugates (ADCs). ADC tumor target expression is essential in investigating the predictive value of Trop-2 and Trop-2 ADC efficacy. Although Trop-2 mRNA expression in NSCLC has been described, protein-level expression is poorly understood. We investigated...

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PMID: 40233061
DOI: 10.1371/journal.pone.0321555

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