Article

High Prevalence of TROP2 Expression Identifies EBV-Positive Gastric Cancer as a Candidate for TROP2-Directed Antibody–Drug Conjugates

2026-08-27

Abstract excerpt

<title>Abstract</title> <p>Trophoblast cell surface antigen 2 (TROP2) is a glycoprotein expressed on epithelial tumor cells and therefore an established target for antibody-drug conjugates (ADCs). Epstein-Barr virus (EBV)-positive gastric cancer is a molecularly distinct subtype characterized by unique immunological features, including frequent responsiveness to immune checkpoint inhibitors (ICIs). Nevertheless,...

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Literature Corpus work: 39355d8e-a182-5258-923b-20b7e3b146c0
DOI: 10.21203/rs.3.rs-10489756/v1

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