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Article

TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis.

The journal of pathology. Clinical research - 1 Sept 2024

Foersch Sebastian, Schmitt Maxime, Litmeyer Anne-Sophie, Tschurtschenthaler Markus, Gress Thomas, Bartsch Detlef K, Pfarr Nicole, Steiger Katja, Denkert Carsten, Jesinghaus Moritz

Abstract excerpt

Antibody-drug conjugates (ADCs) directed to trophoblast cell surface antigen 2 (TROP2) have gained approval as a therapeutic option for advanced triple-negative breast cancer, and TROP2 expression has been linked to unfavourable outcomes in various malignancies. In colorectal carcinoma (CRC), there is still a lack of comprehensive studies on its expression frequency and its prognostic implications in relation to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39177576
DOI: 10.1002/2056-4538.12394
PMCID: PMC11342791

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