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Profiling cancer testis antigens in non–small-cell lung cancer

6 Jul 2016

Abstract excerpt

Cancer testis antigens (CTAs) are of clinical interest as biomarkers and present valuable targets for immunotherapy. To comprehensively characterize the CTA landscape of non-small-cell lung cancer (NSCLC), we compared RNAseq data from 199 NSCLC tissues to the normal transcriptome of 142 samples from 32 different normal organs. Of 232 CTAs currently annotated in the Caner Testis Database (CTdatabase), 96 were...

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PMID: 27699219
DOI: 10.1172/jci.insight.86837

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