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Noninvasive molecular imaging using anti-Trop-2 aptamer for targeted therapy of small cell lung cancer

6 Mar 2025

Abstract excerpt

Recent advancements in antibody-drug conjugates (ADCs) targeting trophoblast surface cell antigen 2 (Trop-2) have brought important progress in the field of targeted therapy. This progress also holds promise for the treatment of small cell lung cancer (SCLC) as anti-Trop-2 therapy appears to have a safe and effective clinical activity in metastatic SCLC patients. However, effective treatments of anti-Trop-2 ADCs...

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PMID: 40050871
DOI: 10.1186/s12951-025-03184-6

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