Article
The relationship between Alzheimer's disease and intracerebral hemorrhage based on Mendelian randomization.
Journal of Alzheimer's disease : JAD - 1 Apr 2025
Shen Yu, Nie Quirui, Xiang WenWen, Chen Shenjian, Cao Qian, Hong Daojun
Abstract excerpt
BackgroundTraditional epidemiologic studies suggest that Alzheimer's disease (AD) may be associated with intracerebral hemorrhage (ICH).ObjectiveTo explore whether there is a causal relationship between AD and ICH and the underlying mechanisms involved.MethodsMendelian randomization (MR) approach was used to explore causal relationships. The genetic instrumental variables of the candidate genetic instrumental...
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