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Article

Association between idiopathic normal pressure hydrocephalus and Alzheimer's disease: a bidirectional Mendelian randomization study.

Scientific reports - 30 Sept 2024

Hu Yuanjun, Cao Chengan, Li Manting, He Haiyong, Luo Lun, Guo Ying

Abstract excerpt

Observational studies have suggested a bidirectional relationship between idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD). However, the causal association between these two neurodegenerative disorders remains unclear. This study aimed to explore the causal relationship between iNPH and AD using a two-sample bidirectional Mendelian randomization (MR) method. Large-scale genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39349954
DOI: 10.1038/s41598-024-72559-w
PMCID: PMC11443089

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