Article
Five Major Psychiatric Disorders and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2022
Wei Tao, Guo Zheng, Wang Zhibin, Li Cancan, Zhu Wei, Zheng Yulu, Yin Yunsi, Mi Yingxin, Xia Xinyi, Hou Haifeng, Tang Yi
Abstract excerpt
BACKGROUND: Extensive studies put forward the association between Alzheimer's disease (AD) and psychiatric disorders; however, it remains unclear whether these associations are causal. OBJECTIVE: We aimed to assess the potential causal relationship between major psychiatric disorders and AD. METHODS: A bidirectional two-sample Mendelian randomization (MR) was applied to evaluate potential causality between five...
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