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Article

Causal relationship between Alzheimer’s disease and cardiovascular disease: a bidirectional Mendelian randomization analysis

2 Sept 2023

Abstract excerpt

Observational studies suggest that cardiovascular disease (CVD) increases the risk of developing Alzheimer’s disease (AD). However, the causal relationship between the two is not clear. This study applied a two-sample bidirectional Mendelian randomization method to explore the causal relationship between CVD and AD. Genome-wide association study (GWAS) data from 46 datasets of European populations (21,982 cases...

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PMID: 37665672
DOI: 10.18632/aging.205013

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