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Article

Systematic comprehension of genomics and mutational landscape of glioma: A goal towards advanced therapeutics.

Neuroscience - 7 May 2025

Dakal Tikam Chand, Ranga Vipin, Kakde Ganesh S, Thakur Mony, Yadav Vinod, Sharma Narendra Kumar, Maurya Pawan Kumar

Abstract excerpt

We provide a systematic understanding of the mutation frequency, genetic profile, and functional implications of genes associated with glioma. Through an analysis of data from the Human Gene Mutation Database (HGMD) and clinical information obtained from a diverse cohort of patients, we identified prominent mutated genes in glioma. PTEN, TP53, EGFR, and MUC16 emerged as the most frequently mutated, each exceeding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40127758
DOI: 10.1016/j.neuroscience.2025.03.047

Genes

TP53
EGFR
MUC16
PPARG
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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