Article
Genetic landscape of cancer: mechanisms, key genes, and therapeutic implications.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Feb 2026
Karnwal Arun, Dutta Joydeep, Aqueel-Ur-Rehman, Al-Tawaha Abdel Rahman Mohammad Said, Nesterova Natalia
Abstract excerpt
Cancer is a complex and heterogeneous disease driven by a multitude of genetic alterations, including mutations, chromosomal rearrangements, and epigenetic modifications. Advances in genomic technologies have significantly enhanced our understanding of the genetic landscape of cancer, enabling the identification of key oncogenes, tumor suppressor genes, and DNA repair mechanisms that influence tumor progression....
Topics
- Humans
- Neoplasms
- Mutation
- Tumor Microenvironment
- Precision Medicine