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Article

Genetic advances in glioma: susceptibility genes and networks.

Current opinion in genetics & development - 1 Jun 2010

Liu Yanhong, Shete Sanjay, Hosking Fay, Robertson Lindsay, Houlston Richard, Bondy Melissa

Abstract excerpt

Recent advances in human genome studies have opened new avenues for the identification of susceptibility genes for many complex genetic disorders, especially in the field of rare cancers such as glioma. To date, eight glioma susceptibility loci have been identified by candidate gene-association studies: PRKDC G6721T, XRCC1 W399R, PARP1 A762V, MGMT F84L, ERCC1 A8092C, ERCC2 Q751K, EGF +61 A/G, and IL13 R110G. Five...

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Source

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Identifiers

PMID: 20211558
DOI: 10.1016/j.gde.2010.02.001
PMCID: PMC2885452

Genes

EGF
ERCC1
ERCC2
MGMT
PARP1
PHLDB1
PRKDC
RTEL1
TERT
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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