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Article

Genomic Profiling in Glioma Patients to Explore Clinically Relevant Markers.

International journal of molecular sciences - 3 Dec 2024

Varachev Viacheslav, Susova Olga, Mitrofanov Alexei, Naskhletashvili David, Krasnov George, Ikonnikova Anna, Bezhanova Svetlana, Semenova Vera, Sevyan Nadezhda, Prozorenko Evgenii, Ammour Yulia, Bekyashev Ali, Nasedkina Tatiana

Abstract excerpt

Gliomas are a heterogeneous group of brain tumors, among which the most aggressive subtype is glioblastoma, accounting for 60% of cases in adults. Available systemic treatment options are few and ineffective, so new approaches to therapies for glioblastoma are in high demand. In total, 131 patients with diffuse glioma were studied. Paired tumor-normal samples were sequenced on the Illumina platform; the panel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39684714
DOI: 10.3390/ijms252313004
PMCID: PMC11641329

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