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Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice

3 Mar 2025

Abstract excerpt

Introduction: Alterations of the adaptive immune system have been shown to impact bone healing and may result in impaired healing in some patients. Apart from T cells, B cells are the key drivers of adaptive immunity. Therefore, their role in age-associated impairments of bone healing might be essential to understand delays during the healing process. B cells are essential for bone formation, and their...

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PMID: 40098964
DOI: 10.3389/fimmu.2025.1511902

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