Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies

Abstract excerpt

BACKGROUND: Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mechanisms underlying the diversity of neuronal and glial tau pathology in different tauopathies are poorly understood. While there is a growing understanding of tauopathy-specific differences in tau isoforms and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Proteomics Techniques and Applications
• Share to Alzheimer's disease research and treatments
• Share to Biotin and Related Studies