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Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of Frontotemporal Dementia

2024-08-20

Abstract excerpt

Diagnosis of Frontotemporal dementia (FTD) and the specific underlying neuropathologies (frontotemporal lobar degeneration; FTLD-Tau and FTLD-TDP) is challenging, and thus fluid biomarkers are needed to improve diagnostic accuracy. We used proximity extension assays to analyze 665 proteins in cerebrospinal fluid (CSF) samples from a multicenter cohort including patients with FTD (n = 189), Alzheimer’s Disease deme...

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Literature Corpus work
fa6b98ae-fc08-51df-82c4-f9f9f8673a9d
DOI
10.1101/2024.08.19.24312100
Open publication

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Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of Frontotemporal DementiaDOI 10.1101/2024.08.19.24312100
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