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Cbfβ: A key regulator in skeletal stem cell differentiation, bone development, and disease

25 Feb 2025

Abstract excerpt

The skeletal system comprises closely related yet functionally distinct bone and cartilage tissues, regulated by a complex network of transcriptional factors and signaling molecules. Among these, core-binding factor subunit beta (Cbfβ) emerges as a critical co-transcriptional factor that stabilizes Runx proteins, playing indispensable roles in skeletal development and homeostasis. Emerging evidence from genetic...

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PMID: 39996474
DOI: 10.1096/fj.202500030r

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Cbfβ: A key regulator in skeletal stem cell differentiation, bone development, and diseasePMID 39996474Read ↗

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