Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal PRDM10 activates essential genes for oocyte-to-embryo transition

24 Feb 2025

Abstract excerpt

PR/SET domain-containing (PRDM) proteins are metazoan-specific transcriptional regulators that play diverse roles in mammalian development and disease. Several members such as PRDM1, PRDM14 and PRDM9, have been implicated in germ cell specification and homoeostasis and are essential to fertility-related processes. Others, such as PRDM14, PRDM15 and PRDM10 play a role in early embryogenesis and embryonic stem cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39994175
DOI: 10.1038/s41467-025-56991-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal PRDM10 activates essential genes for oocyte-to-embryo transitionPMID 39994175Read ↗

Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression programSemantic proximity Read ↗

Unraveling the mysteries of early embryonic arrest: genetic factors and molecular mechanisms.Semantic proximity Read ↗

Genetic Mutations and Non-Genomic Dysregulation in Human Preimplantation Embryo Arrest.Semantic proximity Read ↗

ESRP1-Mediated Alternative Splicing During Oocyte Development is Required for Mouse FertilitySemantic proximity Read ↗

Maternal loss-of-function of Nlrp2 results in failure of epigenetic reprogramming in mouse oocytesSemantic proximity Read ↗

Maternal MLH3 dysfunction drives unexplained recurrent pregnancy loss via impaired oocyte maturation and defective decidualization.Semantic proximity Read ↗

A subcortical maternal complex essential for preimplantation mouse embryogenesis.Semantic proximity Read ↗

MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanismSemantic proximity Read ↗

Meiosis interrupted: the genetics of female infertility via meiotic failureSemantic proximity Read ↗

Novel mutations in genes encoding subcortical maternal complex proteins may cause human embryonic developmental arrest.Semantic proximity Read ↗

The expression level of septin12 is critical for spermiogenesis.Semantic proximity Read ↗

Single cell RNA sequencing reveals the landscape of early female germ cell developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.