Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The expression level of septin12 is critical for spermiogenesis.

The American journal of pathology - 1 May 2009

Lin Ying-Hung, Lin Yung-Ming, Wang Ya-Yun, Yu I-Shing, Lin Yi-Wen, Wang Yun-Han, Wu Ching-Ming, Pan Hsien-An, Chao Shin-Chih, Yen Pauline H, Lin Shu-Wha, Kuo Pao-Lin

Abstract excerpt

Septins belong to a family of polymerizing GTP-binding proteins that are required for many cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis, and cytoskeletal remodeling. One family member, septin12, is expressed specifically in the testis. In this study, we found septin12 expressed in multiple subcellular compartments during terminal differentiation of mouse germ cells. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthenozoospermia
Share to Embryonic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Nick-End Labeling

Share to Infertility, Male

Share to Semen Analysis

Share to Septins

Share to Spermatids

Share to Spermatogenesis

Source

Open in PubMed Open full text

Identifiers

PMID: 19359518
DOI: 10.2353/ajpath.2009.080955
PMCID: PMC2671274

Genes

SEPTIN12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The expression level of septin12 is critical for spermiogenesis.PMID 19359518Read ↗

The role of the septin family in spermiogenesisSemantic proximity Read ↗

SEPT14 complexes maintain sperm morphogenesis and functionSemantic proximity Read ↗

SEPTIN12 genetic variants confer susceptibility to teratozoospermia.Semantic proximity Read ↗

SEPT12-NDC1 Complexes Are Required for Mammalian Spermiogenesis.Semantic proximity Read ↗

Homozygous Loss of Septin12, but not its Haploinsufficiency, Leads to Male Infertility and Fertilization FailureSemantic proximity Read ↗

SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ CellsSemantic proximity Read ↗

The Sept4 septin locus is required for sperm terminal differentiation in mice.Semantic proximity Read ↗

The SEPT12 complex is required for the establishment of a functional sperm head-tail junction.Semantic proximity Read ↗

<i>SEPT12</i>mutations cause male infertility with defective sperm annulusSemantic proximity Read ↗

Biallelic loss‐of‐function mutations in SEPTIN4 ( C17ORF47 ), encoding a conserved annulus protein, cause thin midpiece spermatozoa and male infertility in humansSemantic proximity Read ↗

Maternal PRDM10 activates essential genes for oocyte-to-embryo transitionSemantic proximity Read ↗

Single-nucleotide polymorphism c.474G>A in the SEPT12 gene is a predisposing factor in male infertility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.