Article

MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism

2026-02-14

Abstract excerpt

The molecular mechanisms governing mRNA accumulation during oocyte growth, essential for developmental competence, remain poorly understood. This study investigates the role of Matrin-3 (MATR3), a highly expressed RNA-binding protein in growing oocytes (GOs), using oocyte-specific knockout mouse models and human oocyte maturation arrest (OMA) samples. The results showed that MATR3 was more abundant in GOs than ful...

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Literature Corpus work: a888052a-4f0f-553a-a2c0-ea1d9c21370c
DOI: 10.64898/2026.02.12.705648

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