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Article

A subcortical maternal complex essential for preimplantation mouse embryogenesis.

Developmental cell - 1 Sept 2008

Li Lei, Baibakov Boris, Dean Jurrien

Abstract excerpt

We have identified a subcortical maternal complex (SCMC) that assembles during oocyte growth and is essential for zygotes to progress beyond the first embryonic cell divisions. At least four maternally encoded proteins contribute to this MDa complex: FLOPED, MATER, and TLE6 interact with each other while Filia binds independently to MATER. Although the transcripts encoding these proteins are degraded during...

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Source

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Identifiers

PMID: 18804437
DOI: 10.1016/j.devcel.2008.07.010
PMCID: PMC2597058

Genes

TLE6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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