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Article

Maternal loss-of-function of Nlrp2 results in failure of epigenetic reprogramming in mouse oocytes

2024-06-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: NLRP2 belongs to the subcortical maternal complex (SCMC) of mammalian oocytes and preimplantation embryos. This multiprotein complex, encoded by maternal-effect genes, plays a pivotal role in the zygote-to-embryo transition, early embryogenesis, and epigenetic (re)programming. The maternal inactivation of genes encoding SCMC proteins has been linked to infertili...

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Literature Corpus work
5067675d-54f8-50fc-8ec3-7bb1add7fc83
DOI
10.21203/rs.3.rs-4457414/v1
Open publication

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