Article
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.
Molecular psychiatry - 1 Mar 2017
Trampush J W, Yang M L Z, Yu J, Knowles E, Davies G, Liewald D C, Starr J M, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold A J, Steen V M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson J G, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick K E, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix D K, Need A C, Cirulli E T, Voineskos A N, Stefanis N C, Avramopoulos D, Hatzimanolis A, Arking D E, Smyrnis N, Bilder R M, Freimer N A, Cannon T D, London E, Poldrack R A, Sabb F W, Congdon E, Conley E D, Scult M A, Dickinson D, Straub R E, Donohoe G, Morris D, Corvin A, Gill M, Hariri A R, Weinberger D R, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller M C, Andreassen O A, Deary I J, Glahn D C, Malhotra A K, Lencz T
Abstract excerpt
The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide association study (GWAS) methods. In an attempt to overcome these barriers, the current study utilized GWAS meta-analysis to examine the association of common genetic variation (~8M single-nucleotide polymorphisms (SNP) with minor allele frequency ⩾1%) to general...
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