Correlations of mucin 5B gene polymorphisms and expression levels with the risk of onset of coal workers' pneumoconiosis.

Abstract excerpt

This study investigates the correlations of mucin 5B (MUC5B) rs2672794, rs2075854, and rs868903 polymorphisms and MUC5B expression level with the risk of the onset of coal workers' pneumoconiosis (CWP). Overall, 506 Han Chinese men were included in this study. Among them, 143 were healthy individuals, 132 were dust-exposed workers who underwent health monitoring periodically, and 231 were patients with CWP. The...