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Article

ERCC1 which affects lipids metabolism and actin dynamics in coal workers' pneumoconiosis is a candidate biomarker for early warning and diagnosis.

PloS one - 1 Jan 2024

Deng Hao, Chen Yan, Wu Mali, Zhang Tao

Abstract excerpt

The single-nucleotide polymorphisms of genes related to DNA damage repair and inflammasomes and mutated gene expression in coal workers' pneumoconiosis (CWP) were analysed to identify the risk factors of CWP and potential biomarkers for early warning and diagnosis. Further, mutated gene pathways were analysed based on proteome and metabolome. Han Chinese male subjects were randomly selected and divided into 4 or...

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PMID: 39283905
DOI: 10.1371/journal.pone.0308082
PMCID: PMC11404792

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