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Article

Mannose-binding lectin gene polymorphisms and the development of coal workers' pneumoconiosis in Japan.

American journal of industrial medicine - 1 Jul 2008

Wang Xintao, Ohtsuka Yoshinori, Kimura Kiyonobu, Kaji Hiroshi, Saito Junpei, Tanino Yoshinori, Ishida Takashi, Munakata Mitsuru

Abstract excerpt

BACKGROUND: Infection, immunity and genetic factors play roles in the development of coal worker's pneumoconiosis (CWP) and progressive massive fibrosis (PMF). We investigate whether the genetic polymorphisms of mannose-binding lectin (MBL), one of the key molecules of innate immunity, is associated with the susceptibility to CWP. METHOD: MBL2 polymorphisms (codon54, promoter -221, and -550) were assessed for 197...

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Source

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PMID: 18496832
DOI: 10.1002/ajim.20587

Genes

MBL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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