Article
Polymorphisms in SPARC and coal workers' pneumoconiosis risk in a Chinese population.
PloS one - 1 Jan 2014
Wang Ting, Yang Jingjin, Han Ruhui, Ji Xiaoming, Wu Baiqun, Han Lei, Luo Chen, Fan Jingjing, Zhu Baoli, Ni Chunhui
Abstract excerpt
BACKGROUND: The SPARC is a crucial matricellular protein and may influence the course of various diseases like tumor metastasis and fibrosis. In the present study, we investigated the association between the potential functional polymorphisms in SPARC and coal workers' pneumoconiosis (CWP) risk in a Chinese population. METHODS: Five potentially functional polymorphisms (rs1059279, rs1059829, rs1053411, rs2304052...
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