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Article

Associations of HMGB1 gene polymorphisms with risk of coal workers' pneumoconiosis susceptibility in Chinese Han population.

Inhalation toxicology - 1 Mar 2020

Tang Yijun, Duan Jingzhu, Wang Yun, Yuan Leyong

Abstract excerpt

Background: High-mobility group box 1 (HMGB1) protein plays an important pathogenic role in various diseases such as pulmonary fibrosis. However, the relationship between variation of HMGB1 gene and susceptibility to coal worker's pneumoconiosis (CWP) remains unclear. The objective of the study was to determine the association between HMGB1 polymorphisms and CWP in Chinese Han population.Methods: The genotypes of...

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PMID: 32408780
DOI: 10.1080/08958378.2020.1764153

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