The association of LAMB1 polymorphism and expression changes with the risk of coal workers' pneumoconiosis.

doi:10.1002/tox.22431

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Article

The association of LAMB1 polymorphism and expression changes with the risk of coal workers' pneumoconiosis.

Environmental toxicology - 1 Sept 2017

Ji Xiaoming, Wu Baiqun, Han Ruhui, Yang Jingjin, Ayaaba Esther, Wang Ting, Han Lei, Ni Chunhui

Abstract excerpt

BACKGROUND: Pneumoconiosis is a serious occupational disease worldwide, which is characterized by irreversible and diffuse lung fibrotic lesions. Laminin beta 1(LAMB1) is widely expressed in tissues and it is crucial for both lung morphogenesis and physiological function. In this study, we explored the association between LAMB1 rs4320486 and risk of pneumoconiosis in a Chinese population, as well as its...

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PMID: 28444932
DOI: 10.1002/tox.22431

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LAMB1

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