Article
LRBA Gene Polymorphisms and Risk of Coal Workers' Pneumoconiosis: A Case-Control Study from China.
International journal of environmental research and public health - 27 Sept 2017
Liu Yi, Yang Jingjin, Wu Qiuyun, Han Ruhui, Yan Weiwen, Yuan Jiali, Ji Xiaoming, Li Yan, Yao Wenxi, Ni Chunhui
Abstract excerpt
The lipopolysaccharide (LPS)-responsive beige-like anchor protein (LRBA) is a member of the WDL-BEACH-WD (WBW) gene family. Defects in this gene are associated with the disordered autoimmunity in various diseases, including pulmonary fibrosis. In this study, we investigated the association between the functional polymorphisms in LRBA and risk of coal workers' pneumoconiosis (CWP) in a Chinese population. Three...
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