Article
Association Analysis Identifies New Risk Loci for Coal Workers' Pneumoconiosis in Han Chinese Men.
Toxicological sciences : an official journal of the Society of Toxicology - 1 May 2018
Wang Ting, Li Yan, Zhu Meng, Yao Wenxi, Wu Hongyan, Ji Xiaoming, Hu Zhibin, Shen Hongbing, Fan Xiangshan, Ni Chunhui
Abstract excerpt
Coal worker's pneumoconiosis (CWP) is a debilitating and progressive occupational lung disease resulted from long-term inhalation of airborne silica-containing coal mine dust. Both environmental factors and genetic variations contribute to CWP. Our previous genome-wide association study (GWAS) revealed a tiny fraction of variants with the top associations in Chinese Han population. To identify novel...
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