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Article

Klf10 Regulates the Emergence of Glial Phenotypes During Hypothalamic Development.

Journal of neuroscience research - 1 Feb 2025

Garduño-Tamayo Norma Angelica, Almazán Jorge Luis, Romo-Rodríguez Rubí, Valle-García David, Meza-Sosa Karla F, Pérez-Domínguez Martha, Pelayo Rosana, Pedraza-Alva Gustavo, Pérez-Martínez Leonor

Abstract excerpt

Glial cells play a pivotal role in the Central Nervous System (CNS), constituting most brain cells. Gliogenesis, crucial in CNS development, occurs after neurogenesis. In the hypothalamus, glial progenitors first generate oligodendrocytes and later astrocytes. However, the precise molecular mechanisms governing the emergence of glial lineages in the developing hypothalamus remain incompletely understood. This...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39924964
DOI: 10.1002/jnr.70020
PMCID: PMC11808290

Genes

KLF10
BDNF

Provenance

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