Article
Phenotypic and functional characterization of adult brain neuropoiesis.
Proceedings of the National Academy of Sciences of the United States of America - 28 Jun 2005
Scheffler Bjorn, Walton Noah M, Lin Dean D, Goetz A Katrin, Enikolopov Grigori, Roper Steve N, Steindler Dennis A
Abstract excerpt
The modern concept of neurogenesis in the adult brain is predicated on the premise that multipotent glial cells give rise to new neurons throughout life. Although extensive evidence exists indicating that this is the case, the transition from glial to neuronal phenotype remains poorly understood. A unique monolayer cell-culture system was developed to induce, expose, and recapitulate the entire developmental...
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