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Article

Inflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation.

Molecular neurobiology - 1 Oct 2016

Gabel Sebastien, Koncina Eric, Dorban Gauthier, Heurtaux Tony, Birck Cindy, Glaab Enrico, Michelucci Alessandro, Heuschling Paul, Grandbarbe Luc

Abstract excerpt

Brain inflammation, a common feature in neurodegenerative diseases, is a complex series of events, which can be detrimental and even lead to neuronal death. Nonetheless, several studies suggest that inflammatory signals are also positively influencing neural cell proliferation, survival, migration, and differentiation. Recently, correlative studies suggested that astrocytes are able to dedifferentiate upon injury...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26381429
DOI: 10.1007/s12035-015-9428-3
PMCID: PMC5012156

Genes

TNF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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