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De-regulation of aurora kinases by oncogenic HPV; implications in cancer development and treatment

7 Feb 2025

Abstract excerpt

Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs are the cause of almost all cervical cancers and a sub-set of other epithelial malignancies including head and neck cancers, specifically within the oropharynx. The oncogenic properties of HPV are largely mediated through the viral oncoproteins E6 and E7, which disrupt many cellular pathways to drive uncontrolled cell...

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PMID: 39923999
DOI: 10.1016/j.tvr.2025.200314

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