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Article

A comprehensive spatio-cellular map of the human hypothalamus

5 Feb 2025

Abstract excerpt

Abstract The hypothalamus is a brain region that plays a key role in coordinating fundamental biological functions 1 . However, our understanding of the underlying cellular components and neurocircuitries have, until recently, emerged primarily from rodent studies 2,3 . Here we combine single-nucleus sequencing of 433,369 human hypothalamic cells with spatial transcriptomics, generating a comprehensive...

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PMID: 39910307
DOI: 10.1038/s41586-024-08504-8

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