Article
Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations.
eLife - 21 May 2021
Affinati Alison H, Sabatini Paul V, True Cadence, Tomlinson Abigail J, Kirigiti Melissa, Lindsley Sarah R, Li Chien, Olson David P, Kievit Paul, Myers Martin G, Rupp Alan C
Abstract excerpt
The ventromedial hypothalamic nucleus (VMH) controls diverse behaviors and physiologic functions, suggesting the existence of multiple VMH neural subtypes with distinct functions. Combing translating ribosome affinity purification with RNA-sequencing (TRAP-seq) data with single-nucleus RNA-sequencing (snRNA-seq) data, we identified 24 mouse VMH neuron clusters. Further analysis, including snRNA-seq data from...
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