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Article

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

Nature communications - 31 Aug 2020

Kim Dong Won, Washington Parris Whitney, Wang Zoe Qianyi, Lin Sonia Hao, Sun Changyu, Ismail Basma Taleb, Wang Hong, Jiang Lizhi, Blackshaw Seth

Abstract excerpt

The hypothalamus is a central regulator of many innate behaviors essential for survival, but the molecular mechanisms controlling hypothalamic patterning and cell fate specification are poorly understood. To identify genes that control hypothalamic development, we have used single-cell RNA sequencing (scRNA-Seq) to profile mouse hypothalamic gene expression across 12 developmental time points between embryonic...

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Identifiers

PMID: 32868762
DOI: 10.1038/s41467-020-18231-z
PMCID: PMC7459115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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