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Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis

21 Jan 2025

Abstract excerpt

BACKGROUND: Current research underscores the need to better understand the pathogenic mechanisms and treatment strategies for idiopathic pulmonary fibrosis (IPF). This study aimed to identify key targets involved in the progression of IPF. METHODS: We employed Mendelian randomization (MR) with three genome-wide association studies and four quantitative trait loci datasets to identify key driver genes for IPF....

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 39838395
DOI: 10.1186/s12916-025-03848-y

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