Article

Common and rare variant analyses reveal novel genetic factors underlying Idiopathic Pulmonary Fibrosis and shared aetiology with COVID-19

2024-08-17

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating respiratory disease with limited therapeutic options. We carried out genome-wide association (GWAS), post-GWAS and rare variant analyses utilising the whole genome sequencing data (WGS) from the 100,000 Genomes Project (100kGP) of a cohort of IPF participants ( n =586) to identify novel associations and potential drug targets. Meta-analysis comb...

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Literature Corpus work: a4b8f97a-d6a3-58d8-ac1d-6b11348a80fc
DOI: 10.1101/2024.08.16.24312138

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