Article

Contribution of dominant and recessive model effects to the genetic architecture of Idiopathic Pulmonary Fibrosis

2026-02-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, progressive lung disease with high mortality and few treatment options. Using an additive genetic model, genome-wide association studies (GWAS) have identified multiple risk loci highlighting new genes and pathways of interest. Since IPF risk could also be influenced by non-additive effects, we hypothesised that associat...

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Literature Corpus work: b17d3ca5-ffbb-524d-a266-c19c32b1784c
DOI: 10.64898/2026.02.18.26345897

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