Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases.

Abstract excerpt

BACKGROUND: Although genome-wide association studies (GWAS) have identified many genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and functions remain largely unknown. Many single-cell expression data have become available for IPF, and there is increasing evidence suggesting a shared genetic basis between IPF and other diseases. METHODS: We conducted integrative analyses to...

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