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Article

Association of -607C/A (rs1946518) and -137G/C (rs187238) polymorphisms and immune response in radiation-exposed workers.

International journal of radiation biology - 1 Jan 2025

Surniyantoro Harry Nugroho Eko, Tetriana Devita, Yusuf Darlina, Mailana Wiwin, Indriatama Wijaya Murti, Nasution Khairul Yusuf, Purnami Sofiati, Rahajeng Nastiti, Lusiyanti Yanti, Kisnanto Teja

Abstract excerpt

PURPOSE: Interleukin-18, transforming growth factor-β, and superoxide dismutase are important cytokines and antioxidants in protecting the body from damage caused by radiation exposure through an immune response mechanism. Genetic polymorphisms -607 C/A and -137 G/C are thought to affect the IL-18 cytokine in carrying out its function as a biomarker to indicate adverse conditions due to radiation. The purposes of...

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PMID: 39823224
DOI: 10.1080/09553002.2025.2452293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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