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Article

Review and pooled analysis of studies on -607(C/A) and -137(G/C) polymorphisms in IL-18 and cancer risk.

Medical oncology (Northwood, London, England) - 1 Dec 2011

Mi Yuan-Yuan, Yu Qian-Qian, Yu Meng-Lei, Xu Bin, Zhang Li-Feng, Cheng Wei, Zhang Wei, Hua Li-Xin, Feng Ning-Han

Abstract excerpt

Interleukin-18 (IL-18) is a pleiotropic, pro-inflammatory cytokine with dual effects on tumor development and progression. The -607(C/A) and -137(G/C) polymorphisms in IL-18 gene region have been implicated in cancer risk; however, data from published studies with individually low statistical power are conflicting. To clarify the role of IL-18 -607(C/A) and -137(G/C) genotype in global cancer, we examined all the...

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PMID: 20490717
DOI: 10.1007/s12032-010-9569-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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