Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-18, interleukin-8, and CXCR2 and the risk of silicosis.

Toxicology and industrial health - 1 Oct 2013

Mohebbi Iraj, Rad Isa Abdi, Bagheri Morteza

Abstract excerpt

Molecular mechanisms in the pathogenesis of silicosis are not fully understood. Exposure to crystalline silica leads to the activation of signaling pathways controlling the production and secretion of inflammatory mediators. Inflammatory cytokines are noted as important candidate genes for fibrotic lung diseases. Cytokines, chemokines, and variations of their genes have been associated with upregulation or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Environmental Exposure
Share to Healthy Volunteers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-18

Share to Interleukin-8

Share to Receptors, Interleukin-8B

Share to Silicon Dioxide

Source

Identifiers

PMID: 22661400
DOI: 10.1177/0748233712445048

Genes

CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-18, interleukin-8, and CXCR2 and the risk of silicosis.PMID 22661400Read ↗

TNF-α and IL-1RA polymorphisms and silicosis susceptibility in Chinese workers exposed to silica particles: a case-control study.Semantic proximity Read ↗

Candidate gene polymorphisms associated with silicosis and coal workers' pneumoconiosis: a systematic review and meta-analysis.Semantic proximity Read ↗

Silicosis and its progress influenced by genetic variation on TNF-alpha locus- 308, TNF-alpha and IL-10 cytokine on cement factory workers in Indonesia.Semantic proximity Read ↗

[Relationship between polymorphism of interleukin-8 and silicosis susceptibility].Semantic proximity Read ↗

Cytokine polymorphisms in silicosis and other pneumoconioses.Semantic proximity Read ↗

Polymorphisms in interleukin 17A gene and coal workers' pneumoconiosis risk in a Chinese population.Semantic proximity Read ↗

Association of interleukin-18 promoter polymorphisms with chronic obstructive pulmonary disease in male smokers.Semantic proximity Read ↗

Association of -607C/A (rs1946518) and -137G/C (rs187238) polymorphisms and immune response in radiation-exposed workers.Semantic proximity Read ↗

Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneumoconiosis: a case-control study.Semantic proximity Read ↗

Mechanistically identified suitable biomarkers of exposure, effect, and susceptibility for silicosis and coal-worker's pneumoconiosis: a comprehensive review.Semantic proximity Read ↗

Interleukin gene polymorphisms in pneumoconiosis.Semantic proximity Read ↗

Polymorphisms in inflammasome genes and risk of coal workers' pneumoconiosis in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.