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Article

Investigation of the roles of IL-18 (-607 C/A) and IL-18 (-137 G/C) gene variations in bladder cancer development: case-control study.

Journal of cancer research and clinical oncology - 1 Dec 2021

Alkanli Nevra, Ay Arzu, Cevik Gokhan

Abstract excerpt

BACKGROUND: The purpose of our study is to investigate the roles of IL-18 gene variations in bladder cancer development in Thrace population of Turkey. METHODS: This study was carried out with 103 bladder cancer patients and 81 healthy controls. Genotype distributions of IL-18 (-137 G/C) and IL-18 (-607 C/A) gene variations were determined using polymerase chain reaction (PCR) method. RESULTS: The CC homozygous...

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PMID: 34550451
DOI: 10.1007/s00432-021-03808-y

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